{"id":54034,"date":"2026-06-14T00:00:00","date_gmt":"2026-06-13T17:00:00","guid":{"rendered":"https:\/\/coffeefactz.com\/?p=54034"},"modified":"2026-09-04T19:09:26","modified_gmt":"2026-09-04T12:09:26","slug":"caffeine-an-trong-thuoc","status":"publish","type":"post","link":"https:\/\/coffeefactz.com\/vi\/caffeine-an-trong-thuoc\/","title":{"rendered":"Caffeine \u1ea8n Trong Thu\u1ed1c: V\u00ec Sao Thu\u1ed1c Gi\u1ea3m \u0110au V\u00e0 C\u1ea3m C\u00fam L\u1ea1i Ch\u1ee9a Ch\u1ea5t K\u00edch Th\u00edch?"},"content":{"rendered":"\n

L\u01b0\u1ee3ng caffeine \u1ea9n trong c\u00e1c lo\u1ea1i thu\u1ed1c th\u01b0\u1eddng khi\u1ebfn h\u1ea7u h\u1ebft m\u1ecdi ng\u01b0\u1eddi ho\u00e0n to\u00e0n ng\u1ee1 ng\u00e0ng \u2014 kh\u00f4ng ph\u1ea3i v\u00ec c\u00e1c c\u00f4ng ty d\u01b0\u1ee3c l\u00e9n l\u00fat \u0111\u01b0a v\u00e0o, m\u00e0 v\u00ec h\u1ea7u nh\u01b0 ch\u1eb3ng m\u1ea5y ai ch\u1ecbu \u0111\u1ecdc b\u1ea3ng Th\u00e0nh ph\u1ea7n Ho\u1ea1t ch\u1ea5t (Active Ingredients) tr\u00ean bao b\u00ec thu\u1ed1c gi\u1ea3m \u0111au tr\u01b0\u1edbc khi nu\u1ed1t. Nh\u1eefng c\u00e1i t\u00ean quen thu\u1ed9c nh\u01b0 Excedrin, Midol v\u00e0 m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c tr\u1ecb c\u1ea3m c\u00fam ch\u1ee9a l\u01b0\u1ee3ng caffeine \u0111\u00e1ng k\u1ec3, s\u1eb5n s\u00e0ng t\u01b0\u01a1ng t\u00e1c v\u1edbi m\u1ecdi th\u1ee9c u\u1ed1ng b\u1ea1n \u0111\u00e3 n\u1ea1p v\u00e0o trong ng\u00e0y.<\/p>\n\n\n\n

Hi\u1ec3u r\u00f5 v\u00ec sao caffeine l\u1ea1i c\u00f3 m\u1eb7t \u1edf \u0111\u00f3 \u2014 v\u00e0 ch\u00ednh x\u00e1c l\u00e0 bao nhi\u00eau \u2014 s\u1ebd thay \u0111\u1ed5i c\u00e1ch b\u1ea1n d\u00f9ng thu\u1ed1c. M\u1ed9t khi b\u1ea1n n\u1eafm \u0111\u01b0\u1ee3c c\u01a1 ch\u1ebf sinh h\u1ecdc, d\u00f2ng ch\u1eef nh\u1ecf tr\u00ean nh\u00e3n thu\u1ed1c s\u1ebd kh\u00f4ng c\u00f2n l\u00e0 m\u1edb th\u00f4ng tin th\u1eeba th\u00e3i m\u00e0 tr\u1edf th\u00e0nh c\u00f4ng c\u1ee5 \u0111\u1eafc l\u1ef1c \u0111\u1ec3 b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe.<\/p>\n\n\n\n

V\u00ec Sao Caffeine L\u1ea1i C\u00f3 M\u1eb7t Trong Thu\u1ed1c Gi\u1ea3m \u0110au?<\/h2>\n\n\n\n

Vai tr\u00f2 c\u1ee7a caffeine trong vi\u1ec7c gi\u1ea3m \u0111au kh\u00f4ng \u0111\u01a1n thu\u1ea7n l\u00e0 chi\u00eau tr\u00f2 ti\u1ebfp th\u1ecb \u2014 n\u00f3 v\u1eadn h\u00e0nh qua hai con \u0111\u01b0\u1eddng sinh h\u1ecdc ri\u00eang bi\u1ec7t gi\u00fap vi\u00ean thu\u1ed1c tr\u1ecb \u0111au \u0111\u1ea7u ph\u00e1t huy t\u00e1c d\u1ee5ng m\u1ea1nh m\u1ebd h\u01a1n v\u00e0 nhanh h\u01a1n. Th\u1ee9 nh\u1ea5t, n\u00f3 \u0111\u00f3ng vai tr\u00f2 nh\u01b0 m\u1ed9t ch\u1ea5t co m\u1ea1ch nh\u1eb9, l\u00e0m h\u1eb9p l\u1ea1i c\u00e1c m\u1ea1ch m\u00e1u n\u00e3o \u0111ang gi\u00e3n n\u1edf v\u00e0 s\u01b0ng ph\u1ed3ng v\u1ed1n l\u00e0 ngu\u1ed3n c\u01a1n g\u00e2y ra c\u1ea3m gi\u00e1c \u0111au nh\u1ee9c th\u1ea5u bu\u1ed1t trong c\u00e1c c\u01a1n \u0111au n\u1eeda \u0111\u1ea7u (migraine) hay \u0111au \u0111\u1ea7u do c\u0103ng th\u1eb3ng. Th\u1ee9 hai, n\u00f3 th\u00fac \u0111\u1ea9y c\u01a1 th\u1ec3 h\u1ea5p thu c\u00e1c ho\u1ea1t ch\u1ea5t gi\u1ea3m \u0111au nh\u01b0 paracetamol (acetaminophen) v\u00e0 aspirin nhanh h\u01a1n, \u0111\u01b0a thu\u1ed1c \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111i\u1ec1u tr\u1ecb trong huy\u1ebft t\u01b0\u01a1ng s\u1edbm h\u01a1n nhi\u1ec1u so v\u1edbi khi d\u00f9ng \u0111\u01a1n l\u1ebb.<\/p>\n\n\n\n

\u0110i\u1ec3m th\u1ee9 hai n\u00e0y r\u1ea5t \u0111\u00e1ng \u0111\u1ec3 ch\u00fang ta suy ng\u1eabm. Kh\u00f4ng ph\u1ea3i caffeine ch\u1ec9 \u0111\u01a1n thu\u1ea7n “h\u1ed7 tr\u1ee3” \u2014 n\u00f3 th\u1ef1c s\u1ef1 khu\u1ebfch \u0111\u1ea1i \u0111\u00e1ng k\u1ec3 n\u0103ng l\u1ef1c xoa d\u1ecbu c\u01a1n \u0111au c\u1ee7a c\u00e1c lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c ph\u1ed1i h\u1ee3p c\u00f9ng. M\u1ed9t b\u00e0i t\u1ed5ng quan d\u01b0\u1ee3c l\u00fd h\u1ecdc \u0111\u00e3 n\u00eau r\u00f5:<\/p>\n\n\n\n

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“Caffeine l\u00e0 m\u1ed9t ch\u1ea5t b\u1ed5 tr\u1ee3 gi\u1ea3m \u0111au hi\u1ec7u qu\u1ea3 v\u00ec n\u00f3 gia t\u0103ng t\u00e1c d\u1ee5ng ch\u1ed1ng c\u1ea3m th\u1ee5 \u0111au c\u1ee7a c\u00e1c thu\u1ed1c NSAID\u2026”<\/strong><\/u><\/a><\/p>\n\n<\/blockquote>\n\n\n\n

\u0110\u00f3 l\u00e0 l\u00fd do v\u00ec sao caffeine lu\u00f4n xu\u1ea5t hi\u1ec7n trong c\u00e1c d\u00f2ng thu\u1ed1c \u0111\u1eb7c tr\u1ecb ch\u1ee9ng \u0111au n\u1eeda \u0111\u1ea7u v\u00e0 \u0111au \u0111\u1ea7u c\u0103ng th\u1eb3ng \u2014 c\u1ea3 hai b\u1ec7nh l\u00fd \u0111\u1ec1u li\u00ean quan \u0111\u1ebfn nh\u1eefng bi\u1ebfn \u0111\u1ed5i m\u1ea1ch m\u00e1u m\u00e0 t\u1ed1c \u0111\u1ed9 c\u1eaft c\u01a1n l\u00e0 y\u1ebfu t\u1ed1 s\u1ed1ng c\u00f2n. T\u00e1c \u0111\u1ed9ng co m\u1ea1ch l\u00e0m gi\u1ea3m b\u1edbt \u00e1p l\u1ef1c c\u01a1 h\u1ecdc l\u00ean c\u00e1c th\u1ee5 th\u1ec3 th\u1ea7n kinh, trong khi kh\u1ea3 n\u0103ng t\u0103ng c\u01b0\u1eddng h\u1ea5p thu gi\u00fap paracetamol ho\u1eb7c aspirin k\u1ecbp th\u1eddi d\u1eadp t\u1eaft c\u01a1n \u0111au tr\u01b0\u1edbc khi n\u00f3 b\u00f9ng ph\u00e1t d\u1eef d\u1ed9i h\u01a1n.<\/p>\n\n\n\n

\u0110i\u1ec1u khi\u1ebfn nhi\u1ec1u ng\u01b0\u1eddi b\u1ea5t ng\u1edd nh\u1ea5t l\u00e0: caffeine kh\u00f4ng ph\u1ea3i l\u00e0 ch\u1ea5t ph\u1ee5 gia gi\u1ea5u m\u1eb7t. N\u00f3 l\u00e0 m\u1ed9t ho\u1ea1t ch\u1ea5t ch\u00ednh th\u1ee9c v\u1edbi m\u1ee5c \u0111\u00edch \u0111i\u1ec1u tr\u1ecb r\u00f5 r\u00e0ng v\u00e0 h\u00e0m l\u01b0\u1ee3ng miligram \u0111\u01b0\u1ee3c in c\u00f4ng khai tr\u00ean b\u1ea3ng Th\u00f4ng tin D\u01b0\u1ee3c ph\u1ea9m (Drug Facts) c\u1ee7a m\u1ecdi s\u1ea3n ph\u1ea9m kh\u00f4ng k\u00ea \u0111\u01a1n theo quy \u0111\u1ecbnh ph\u00e1p lu\u1eadt. B\u1ea1n lu\u00f4n c\u00f3 quy\u1ec1n ti\u1ebfp c\u1eadn th\u00f4ng tin n\u00e0y \u2014 ch\u1ec9 l\u00e0 b\u1ea1n ch\u01b0a t\u1eebng \u0111\u1ec3 \u00fd t\u00ecm ki\u1ebfm m\u00e0 th\u00f4i.<\/p>\n\n\n\n

D\u01b0\u1edbi \u0111\u00e2y l\u00e0 h\u00ecnh \u1ea3nh ph\u00e2n t\u00edch tr\u1ef1c quan c\u00e1ch th\u1ee9c hai c\u01a1 ch\u1ebf n\u00e0y c\u00f9ng ph\u1ed1i h\u1ee3p trong c\u01a1 th\u1ec3 b\u1ea1n:<\/p>\n\n\n\n

\"Infographic<\/figure>\n\n\n\n
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Nh\u1eefng Lo\u1ea1i Thu\u1ed1c Kh\u00f4ng K\u00ea \u0110\u01a1n (OTC) N\u00e0o Th\u01b0\u1eddng Ch\u1ee9a Caffeine?<\/h2>\n\n\n\n

C\u00e1c lo\u1ea1i thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n ch\u1ee9a caffeine ph\u1ed5 bi\u1ebfn h\u01a1n nhi\u1ec1u ng\u01b0\u1eddi ngh\u0129, v\u00e0 li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a ch\u00fang kh\u00f4ng h\u1ec1 nh\u1ecf. Bi\u1ebft r\u00f5 s\u1ea3n ph\u1ea9m n\u00e0o c\u00f3 caffeine \u2014 v\u00e0 ch\u00ednh x\u00e1c l\u00e0 bao nhi\u00eau \u2014 l\u00e0 n\u1ec1n t\u1ea3ng \u0111\u1ec3 ki\u1ec3m so\u00e1t t\u1ed5ng l\u01b0\u1ee3ng n\u1ea1p trong ng\u00e0y. Danh s\u00e1ch n\u00e0y \u0111\u01b0\u1ee3c chia th\u00e0nh hai nh\u00f3m th\u1ef1c t\u1ebf: m\u1ed9t b\u00ean l\u00e0 thu\u1ed1c gi\u1ea3m \u0111au v\u00e0 gi\u1ea3m tri\u1ec7u ch\u1ee9ng kinh nguy\u1ec7t, m\u1ed9t b\u00ean l\u00e0 thu\u1ed1c c\u1ea3m c\u00fam k\u1ebft h\u1ee3p vi\u00ean u\u1ed1ng t\u0103ng c\u01b0\u1eddng s\u1ef1 t\u1ec9nh t\u00e1o.<\/p>\n\n\n\n

Excedrin V\u00e0 Midol: Nh\u1eefng Li\u1ec1u L\u01b0\u1ee3ng T\u00edch Ti\u1ec3u Th\u00e0nh \u0110\u1ea1i R\u1ea5t Nhanh<\/h3>\n\n\n\n

Excedrin Extra Strength v\u00e0 d\u00f2ng Excedrin Migraine \u0111\u1ec1u ch\u1ee9a kho\u1ea3ng 65mg caffeine trong m\u1ed7i vi\u00ean n\u00e9n. Con s\u1ed1 \u0111\u00f3 nghe c\u00f3 v\u1ebb khi\u00eam t\u1ed1n \u2014 cho \u0111\u1ebfn khi b\u1ea1n u\u1ed1ng theo li\u1ec1u chu\u1ea9n 2 vi\u00ean m\u1ed9t l\u1ea7n. Hai vi\u00ean thu\u1ed1c cung c\u1ea5p ngay 130mg caffeine trong m\u1ed9t l\u1ea7n u\u1ed1ng, \u0111\u00e3 v\u01b0\u1ee3t qua l\u01b0\u1ee3ng caffeine c\u1ee7a m\u1ed9t t\u00e1ch c\u00e0 ph\u00ea pha 240ml (8 oz) ti\u00eau chu\u1ea9n. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u d\u01b0\u1ee3c l\u00fd l\u00e2m s\u00e0ng Voicu v\u00e0 c\u1ed9ng s\u1ef1<\/strong><\/u><\/a> \u0111\u00e3 x\u00e1c nh\u1eadn c\u00f4ng th\u1ee9c \u0111\u1ecbnh li\u1ec1u n\u00e0y:<\/p>\n\n\n\n

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“…Excedrin\u00ae, m\u1ed9t lo\u1ea1i thu\u1ed1c ph\u1ed1i h\u1ee3p li\u1ec1u c\u1ed1 \u0111\u1ecbnh ch\u1ee9a 250 mg ASA, 250 mg PAR v\u00e0 65 mg CAF.”<\/em> \u2014 Voicu v\u00e0 c\u1ed9ng s\u1ef1, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u d\u01b0\u1ee3c l\u00fd l\u00e2m s\u00e0ng<\/p>\n\n<\/blockquote>\n\n\n\n

Midol Complete c\u0169ng \u00e1p d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p t\u01b0\u01a1ng t\u1ef1. M\u1ed7i vi\u00ean nang ch\u1ee9a kho\u1ea3ng 60mg caffeine, \u0111\u01b0\u1ee3c th\u00eam v\u00e0o ch\u1ee7 \u0111\u00edch nh\u1eb1m gi\u1ea3i quy\u1ebft hai tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn nh\u1ea5t trong k\u1ef3 kinh nguy\u1ec7t: \u0111\u1ea7y h\u01a1i ph\u00f9 n\u1ec1 v\u00e0 m\u1ec7t m\u1ecfi. Logic n\u00e0y gi\u1ed1ng h\u1ec7t nh\u01b0 trong vi\u00ean thu\u1ed1c \u0111au \u0111\u1ea7u \u2014 caffeine \u0111\u00f3ng vai tr\u00f2 k\u00e9p v\u1eeba l\u00e0 ch\u1ea5t l\u1ee3i ti\u1ec3u nh\u1eb9 v\u1eeba l\u00e0 ch\u1ea5t b\u1ed5 tr\u1ee3 ti\u1ebfp th\u00eam n\u0103ng l\u01b0\u1ee3ng. Nh\u01b0ng v\u1edbi m\u1ed9t ng\u01b0\u1eddi v\u1ed1n \u0111\u00e3 u\u1ed1ng 2\u20133 ly c\u00e0 ph\u00ea m\u1ed7i ng\u00e0y, 60mg m\u1ed7i vi\u00ean l\u00e0 m\u1ed9t s\u1ef1 c\u1ed9ng h\u01b0\u1edfng r\u1ea5t \u0111\u00e1ng k\u1ec3 v\u00e0o t\u1ed5ng l\u01b0\u1ee3ng n\u1ea1p, ch\u1ee9 kh\u00f4ng ph\u1ea3i m\u1ed9t con s\u1ed1 v\u1ebft c\u00f3 th\u1ec3 ng\u00f3 l\u01a1.<\/p>\n\n\n\n

B\u1ea3ng d\u01b0\u1edbi \u0111\u00e2y so s\u00e1nh tr\u1ef1c quan hai d\u00f2ng s\u1ea3n ph\u1ea9m ph\u1ed5 bi\u1ebfn n\u00e0y:<\/p>\n\n\n\n

S\u1ea3n Ph\u1ea9m<\/th>Caffeine M\u1ed7i Vi\u00ean N\u00e9n \/ Vi\u00ean Nang<\/th>Li\u1ec1u D\u00f9ng Ti\u00eau Chu\u1ea9n<\/th>T\u1ed5ng Caffeine M\u1ed7i Li\u1ec1u<\/th>Ho\u1ea1t Ch\u1ea5t Gi\u1ea3m \u0110au Ch\u00ednh<\/th>M\u1ee5c \u0110\u00edch S\u1eed D\u1ee5ng<\/th><\/tr><\/thead>
Excedrin Extra Strength \/ Migraine<\/td>~65 mg<\/td>2 vi\u00ean<\/td>~130 mg<\/td>Acetaminophen (Paracetamol) 250 mg, Aspirin 250 mg<\/td>Gi\u1ea3m \u0111au \u0111\u1ea7u, c\u1eaft c\u01a1n \u0111au n\u1eeda \u0111\u1ea7u<\/td><\/tr>
Midol Complete<\/td>~60 mg<\/td>1 vi\u00ean nang<\/td>~60 mg<\/td>Acetaminophen 500 mg, Pyrilamine maleate 15 mg<\/td>\u0110au b\u1ee5ng kinh, \u0111\u1ea7y h\u01a1i, m\u1ec7t m\u1ecfi<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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Thu\u1ed1c C\u1ea3m C\u00fam, Vi\u00ean U\u1ed1ng T\u1ec9nh T\u00e1o V\u00e0 Th\u1ef1c Ph\u1ea9m B\u1ed5 Sung Ch\u1ee9a Caffeine<\/h3>\n\n\n\n

C\u00e1c lo\u1ea1i thu\u1ed1c c\u1ea3m c\u00fam ban ng\u00e0y chi\u1ebfm m\u1ed9t v\u1ecb tr\u00ed kh\u00e1c tr\u00ean b\u1ea3n \u0111\u1ed3 caffeine trong d\u01b0\u1ee3c ph\u1ea9m. M\u1ed9t s\u1ed1 c\u00f4ng th\u1ee9c DayQuil, Theraflu v\u00e0 c\u00e1c s\u1ea3n ph\u1ea9m t\u01b0\u01a1ng \u0111\u01b0\u01a1ng th\u01b0\u1eddng \u0111\u01b0\u1ee3c b\u1ed5 sung caffeine ch\u1ee7 y\u1ebfu \u0111\u1ec3 \u0111\u1ed1i tr\u1ecdng v\u1edbi c\u01a1n bu\u1ed3n ng\u1ee7 l\u1edd \u0111\u1edd do c\u00e1c thu\u1ed1c kh\u00e1ng histamine th\u1ebf h\u1ec7 c\u0169 t\u1ea1o ra. H\u00e0m l\u01b0\u1ee3ng dao \u0111\u1ed9ng t\u00f9y theo t\u1eebng nh\u00e3n hi\u1ec7u v\u00e0 c\u00f4ng th\u1ee9c, \u0111i\u1ec1u \u0111\u00f3 c\u00f3 ngh\u0129a vi\u1ec7c \u0111\u1ecdc nh\u00e3n l\u00e0 b\u1eaft bu\u1ed9c \u2014 kh\u00f4ng c\u00f3 con s\u1ed1 m\u1eb7c \u0111\u1ecbnh chung cho nh\u00f3m n\u00e0y.<\/p>\n\n\n\n

Trong khi \u0111\u00f3, h\u00e0m l\u01b0\u1ee3ng caffeine trong c\u00e1c vi\u00ean u\u1ed1ng t\u0103ng \u0111\u1ed9 t\u1ec9nh t\u00e1o l\u1ea1i l\u00e0 m\u1ed9t c\u00e2u chuy\u1ec7n ho\u00e0n to\u00e0n kh\u00e1c. NoDoz v\u00e0 Vivarin ch\u1ee9a t\u1edbi 200mg caffeine trong m\u1ed7i vi\u00ean \u2014 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi kho\u1ea3ng 2 t\u00e1ch c\u00e0 ph\u00ea ti\u00eau chu\u1ea9n g\u00f3i g\u1ecdn trong m\u1ed9t vi\u00ean duy nh\u1ea5t. Nh\u1eefng s\u1ea3n ph\u1ea9m n\u00e0y kh\u00f4ng h\u1ec1 gi\u1ea5u gi\u1ebfm c\u01a1 ch\u1ebf c\u1ee7a ch\u00fang; caffeine ch\u00ednh l\u00e0 ho\u1ea1t ch\u1ea5t duy nh\u1ea5t. Nh\u01b0ng ng\u01b0\u1eddi ta th\u01b0\u1eddng t\u00ecm \u0111\u1ebfn ch\u00fang khi \u0111ang b\u1ecb c\u1ea3m m\u1ec7t m\u1ecfi ho\u1eb7c trong nh\u1eefng ng\u00e0y l\u00e0m vi\u1ec7c d\u00e0i m\u00e0 b\u1ea3n th\u00e2n v\u1ed1n \u0111\u00e3 u\u1ed1ng s\u1eb5n c\u00e0 ph\u00ea, v\u00f4 t\u00ecnh t\u1ea1o n\u00ean con \u0111\u01b0\u1eddng d\u1eabn th\u1eb3ng \u0111\u1ebfn t\u00ecnh tr\u1ea1ng qu\u00e1 t\u1ea3i.<\/p>\n\n\n\n

Th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng h\u1ed7 tr\u1ee3 gi\u1ea3m c\u00e2n v\u00e0 t\u0103ng l\u1ef1c b\u1ed5 sung th\u00eam m\u1ed9t ngu\u1ed3n \u1ea9n l\u1edbn. Nhi\u1ec1u s\u1ea3n ph\u1ea9m d\u1ef1a v\u00e0o caffeine ho\u1eb7c c\u00e1c ch\u1ea5t k\u00edch th\u00edch th\u1ea3o d\u01b0\u1ee3c m\u00e0 kh\u00f4ng in ch\u1eef “caffeine” r\u00f5 r\u00e0ng tr\u00ean b\u1ea3ng th\u00e0nh ph\u1ea7n ch\u00ednh. Chi\u1ebft xu\u1ea5t tr\u00e0 xanh, guarana v\u00e0 h\u1ea1t kola l\u00e0 nh\u1eefng c\u00e1i t\u00ean th\u1ef1c v\u1eadt ph\u1ed5 bi\u1ebfn nh\u1ea5t \u2014 t\u1ea5t c\u1ea3 \u0111\u1ec1u cung c\u1ea5p l\u01b0\u1ee3ng caffeine th\u1ef1c th\u1ee5, nh\u01b0ng d\u01b0\u1edbi l\u1edbp \u00e1o th\u1ef1c v\u1eadt \u00edt g\u00e2y ra s\u1ef1 c\u1ea3nh gi\u00e1c nh\u01b0 ch\u1eef “caffeine”.<\/p>\n\n\n\n

M\u1ed9t ph\u00e2n t\u00edch trong ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean 63 s\u1ea3n ph\u1ea9m gi\u1ea3m c\u00e2n v\u00e0 thu\u1ed1c c\u1ea3m \u0111a tri\u1ec7u ch\u1ee9ng ph\u00e1t hi\u1ec7n ra r\u1eb1ng 33 s\u1ea3n ph\u1ea9m trong s\u1ed1 \u0111\u00f3 \u2014 chi\u1ebfm kho\u1ea3ng 52% \u2014 c\u00f3 ch\u1ee9a caffeine<\/strong><\/u><\/a>. H\u01a1n m\u1ed9t n\u1eeda s\u1ed1 s\u1ea3n ph\u1ea9m trong m\u1ed9t nh\u00f3m m\u1eb7t h\u00e0ng th\u00f4ng th\u01b0\u1eddng \u0111ang \u00e2m th\u1ea7m \u0111\u00f3ng g\u00f3p v\u00e0o l\u01b0\u1ee3ng caffeine h\u00e0ng ng\u00e0y c\u1ee7a b\u1ea1n.<\/p>\n\n\n\n

To\u00e0n b\u1ed9 l\u01b0\u1ee3ng caffeine t\u1eeb thu\u1ed1c n\u00e0y s\u1ebd ch\u1ed3ng ch\u1ea5t l\u00ean b\u1ea5t k\u1ef3 t\u00e1ch c\u00e0 ph\u00ea, ly tr\u00e0, lon n\u01b0\u1edbc ng\u1ecdt hay n\u01b0\u1edbc t\u0103ng l\u1ef1c n\u00e0o b\u1ea1n n\u1ea1p v\u00e0o. Ph\u00e9p t\u00ednh c\u1ed9ng d\u1ed3n s\u1ebd b\u1eaft k\u1ecbp v\u00e0 l\u00e0m c\u01a1 th\u1ec3 b\u1ea1n qu\u00e1 t\u1ea3i nhanh h\u01a1n b\u1ea1n t\u01b0\u1edfng.<\/p>\n\n\n\n

V\u00f9ng Nguy Hi\u1ec3m Khi K\u1ebft H\u1ee3p C\u00e0 Ph\u00ea V\u00e0 Thu\u1ed1c<\/h2>\n\n\n\n

T\u00ecnh tr\u1ea1ng qu\u00e1 t\u1ea3i caffeine th\u01b0\u1eddng kh\u00f4ng b\u1eaft ngu\u1ed3n t\u1eeb nh\u1eefng quy\u1ebft \u0111\u1ecbnh li\u1ec1u l\u0129nh \u2014 n\u00f3 x\u1ea3y ra v\u00ec c\u00e1c li\u1ec1u l\u01b0\u1ee3ng v\u1ed1n v\u00f4 h\u00ecnh cho t\u1edbi khi b\u1ea1n \u0111\u1eb7t b\u00fat l\u00e0m ph\u00e9p c\u1ed9ng. H\u00e3y th\u1eed h\u00ecnh dung m\u1ed9t k\u1ecbch b\u1ea3n r\u1ea5t \u0111\u1eddi th\u01b0\u1eddng: b\u1ea1n u\u1ed1ng 2 vi\u00ean Excedrin \u0111\u1ec3 tr\u1ecb c\u01a1n \u0111au \u0111\u1ea7u (n\u1ea1p 130mg caffeine), r\u1ed3i sau \u0111\u00f3 u\u1ed1ng k\u00e8m th\u00eam m\u1ed9t ly c\u00e0 ph\u00ea l\u1edbn 590ml (20 oz) (cung c\u1ea5p kho\u1ea3ng 300\u2013400mg t\u00f9y \u0111\u1ed9 rang v\u00e0 c\u00e1ch pha). Ch\u1ec9 trong m\u1ed9t bu\u1ed5i s\u00e1ng, tr\u01b0\u1edbc c\u1ea3 khi b\u1ea1n \u0103n tr\u01b0a, t\u1ed5ng l\u01b0\u1ee3ng caffeine \u0111\u00e3 ch\u1ea1m m\u1ed1c 430 \u0111\u1ebfn 530mg. H\u01b0\u1edbng d\u1eabn khuy\u1ebfn c\u00e1o c\u1ee7a FDA<\/strong><\/u><\/a> d\u00e0nh cho ng\u01b0\u1eddi l\u1edbn kh\u1ecfe m\u1ea1nh \u0111\u1eb7t m\u1ee9c tr\u1ea7n an to\u00e0n \u1edf ng\u01b0\u1ee1ng 400mg m\u1ed7i ng\u00e0y:<\/p>\n\n\n\n

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“Ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh kh\u1ecfe m\u1ea1nh c\u00f3 th\u1ec3 ti\u00eau th\u1ee5 t\u1ed1i \u0111a 400 miligram m\u1ed7i ng\u00e0y\u2026”<\/em> \u2014 C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA)<\/p>\n\n<\/blockquote>\n\n\n\n

B\u1ea1n \u0111\u00e3 v\u00f4 t\u00ecnh v\u01b0\u1ee3t qua ng\u01b0\u1ee1ng n\u00e0y khi ng\u00e0y m\u1edbi ch\u1ec9 tr\u00f4i qua \u0111\u01b0\u1ee3c m\u1ed9t n\u1eeda.<\/p>\n\n\n\n

Nh\u1eefng h\u1ec7 qu\u1ea3 tr\u01b0\u1edbc m\u1eaft ho\u00e0n to\u00e0n c\u00f3 th\u1ec3 d\u1ef1 \u0111o\u00e1n \u0111\u01b0\u1ee3c: c\u1ea3m gi\u00e1c b\u1ed3n ch\u1ed3n run r\u1ea9y, tim \u0111\u1eadp nhanh th\u00ecnh th\u1ecbch, lo \u00e2u b\u1ea5t an, t\u0103ng huy\u1ebft \u00e1p v\u00e0 kh\u00f3 ch\u00ecm v\u00e0o gi\u1ea5c ng\u1ee7 ban \u0111\u00eam. Kh\u00f4ng tri\u1ec7u ch\u1ee9ng n\u00e0o trong s\u1ed1 \u0111\u00f3 t\u1ea1o cho b\u1ea1n c\u1ea3m gi\u00e1c gi\u1ed1ng nh\u01b0 t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c \u2014 ch\u00fang cho c\u1ea3m gi\u00e1c h\u1ec7t nh\u01b0 b\u1ea1n \u0111ang b\u1ecb c\u0103ng th\u1eb3ng c\u00f4ng vi\u1ec7c hay do u\u1ed1ng h\u01a1i nhi\u1ec1u c\u00e0 ph\u00ea, v\u00e0 \u0111\u00f3 ch\u00ednh l\u00e0 l\u00fd do s\u1ef1 li\u00ean k\u1ebft n\u00e0y th\u01b0\u1eddng b\u1ecb b\u1ecf qua.<\/p>\n\n\n\n

\u0110i\u1ec1u l\u00e0m cho m\u1ed1c 400mg tr\u1edf n\u00ean ph\u1ee9c t\u1ea1p h\u01a1n th\u1ef1c t\u1ebf l\u00e0 con s\u1ed1 n\u00e0y ch\u1ec9 l\u00e0 m\u1ee9c trung b\u00ecnh c\u1ee7a d\u00e2n s\u1ed1, kh\u00f4ng ph\u1ea3i ng\u01b0\u1ee1ng ch\u1ecbu \u0111\u1ef1ng ri\u00eang cho t\u1eebng c\u00e1 nh\u00e2n. Kho\u1ea3ng 25% d\u00e2n s\u1ed1 mang bi\u1ebfn th\u1ec3 gen khi\u1ebfn h\u1ecd tr\u1edf th\u00e0nh nh\u00f3m ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a ch\u1eadm qua enzyme gan CYP1A2 \u2014 h\u1ecd thanh l\u1ecdc caffeine ch\u1eadm h\u01a1n g\u1ea5p 4 l\u1ea7n so v\u1edbi nh\u00f3m chuy\u1ec3n h\u00f3a nhanh. M\u1ed9t li\u1ec1u l\u01b0\u1ee3ng m\u00e0 ng\u01b0\u1eddi b\u1ea1n c\u1ee7a b\u1ea1n x\u1eed l\u00fd v\u00e0 qu\u00ean b\u1eb5ng sau 3 gi\u1edd th\u00ec v\u1eabn c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c k\u00edch th\u00edch trong c\u01a1 th\u1ec3 ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a ch\u1eadm sau 8 gi\u1edd, khu\u1ebfch \u0111\u1ea1i c\u01a1n b\u1ed3n ch\u1ed3n, m\u1ea5t ng\u1ee7 v\u00e0 \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c r\u1ea5t l\u00e2u sau khi t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au c\u1ee7a thu\u1ed1c \u0111\u00e3 tan bi\u1ebfn.<\/p>\n\n\n\n

Thai k\u1ef3 l\u1ea1i b\u1ed5 sung th\u00eam m\u1ed9t t\u1ea7ng ki\u1ec3m so\u00e1t kh\u1eaft khe kh\u00e1c. C\u00e1c t\u1ed5 ch\u1ee9c y t\u1ebf l\u1edbn khuy\u1ebfn ngh\u1ecb ph\u1ee5 n\u1eef mang thai n\u00ean gi\u1edbi h\u1ea1n caffeine \u1edf m\u1ee9c 200mg m\u1ed7i ng\u00e0y<\/u><\/b><\/a> \u2014 b\u1eb1ng m\u1ed9t n\u1eeda m\u1ee9c th\u00f4ng th\u01b0\u1eddng. M\u1ed9t li\u1ec1u thu\u1ed1c gi\u1ea3m \u0111au ch\u1ee9a caffeine duy nh\u1ea5t k\u1ebft h\u1ee3p v\u1edbi m\u1ed9t t\u00e1ch c\u00e0 ph\u00ea nh\u1ecf \u0111\u00e3 \u0111\u1ee7 \u0111\u1ec3 ch\u1ea1m t\u1edbi ng\u01b0\u1ee1ng tr\u1ea7n n\u00e0y tr\u01b0\u1edbc khi t\u00ednh \u0111\u1ebfn b\u1ea5t k\u1ef3 m\u00f3n \u0103n n\u00e0o kh\u00e1c.<\/p>\n\n\n\n

C\u00e1c ngu\u1ed3n \u1ea9n c\u1ed9ng d\u1ed3n l\u00e0m v\u1ea5n \u0111\u1ec1 th\u00eam nan gi\u1ea3i. M\u1ed9t lon n\u01b0\u1edbc ng\u1ecdt c\u00f3 ga b\u1ed5 sung th\u00eam kho\u1ea3ng 35mg. M\u1ed9t lon n\u01b0\u1edbc t\u0103ng l\u1ef1c \u0111\u00f3ng g\u00f3p t\u1eeb 80 \u0111\u1ebfn 150mg. Ngay c\u1ea3 m\u1ed9t thanh socola c\u0169ng mang theo m\u1ed9t l\u01b0\u1ee3ng caffeine khi\u00eam t\u1ed1n nh\u01b0ng c\u00f3 th\u1eadt. Kh\u00f4ng m\u00f3n n\u00e0o t\u1ea1o cho b\u1ea1n c\u1ea3m gi\u00e1c nh\u01b0 “v\u1eeba u\u1ed1ng caffeine” gi\u1ed1ng nh\u01b0 m\u1ed9t t\u00e1ch c\u00e0 ph\u00ea, nh\u01b0ng t\u1ea5t c\u1ea3 \u0111\u1ec1u \u0111\u01b0\u1ee3c c\u01a1 th\u1ec3 ghi nh\u1eadn.<\/p>\n\n\n\n

T\u01b0\u01a1ng t\u00e1c thu\u1ed1c l\u00e0 t\u1ea7ng r\u1ee7i ro cu\u1ed1i c\u00f9ng nh\u01b0ng \u00edt \u0111\u01b0\u1ee3c quan t\u00e2m \u0111\u00fang m\u1ee9c. M\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh \u2014 ciprofloxacin l\u00e0 v\u00ed d\u1ee5 kinh \u0111i\u1ec3n \u2014 \u1ee9c ch\u1ebf enzyme CYP1A2, ch\u00ednh l\u00e0 con \u0111\u01b0\u1eddng \u0111\u00e0o th\u1ea3i caffeine kh\u1ecfi c\u01a1 th\u1ec3 b\u1ea1n. Thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng c\u0169ng c\u00f3 t\u00e1c \u0111\u1ed9ng l\u00e0m ch\u1eadm t\u01b0\u01a1ng t\u1ef1. N\u1ebfu b\u1ea1n \u0111ang s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y, l\u01b0\u1ee3ng caffeine t\u1eeb vi\u00ean thu\u1ed1c gi\u1ea3m \u0111au s\u1ebd t\u1ed3n l\u01b0u l\u00e2u h\u01a1n v\u00e0 \u1edf n\u1ed3ng \u0111\u1ed9 hi\u1ec7u d\u1ee5ng cao h\u01a1n nhi\u1ec1u so v\u1edbi d\u1ef1 t\u00ednh \u0111\u01a1n thu\u1ea7n tr\u00ean nh\u00e3n.<\/p>\n\n\n\n

S\u1ef1 k\u1ebft h\u1ee3p nguy hi\u1ec3m nh\u1ea5t li\u00ean quan \u0111\u1ebfn c\u00e1c thu\u1ed1c th\u00f4ng m\u0169i tr\u1ecb ng\u1ea1t xoang. Ho\u1ea1t ch\u1ea5t Pseudoephedrine, c\u00f3 m\u1eb7t trong nhi\u1ec1u c\u00f4ng th\u1ee9c thu\u1ed1c c\u1ea3m c\u00fam ban ng\u00e0y, b\u1ea3n th\u00e2n n\u00f3 \u0111\u00e3 l\u00e0m t\u0103ng nh\u1ecbp tim v\u00e0 t\u0103ng huy\u1ebft \u00e1p. Vi\u1ec7c k\u1ebft h\u1ee3p n\u00f3 v\u1edbi thu\u1ed1c ch\u1ee9a caffeine \u2014 ho\u1eb7c v\u1edbi c\u00e0 ph\u00ea t\u1eeb b\u1ea5t k\u1ef3 ngu\u1ed3n n\u00e0o \u2014 s\u1ebd nh\u00e2n \u0111\u00f4i g\u00e1nh n\u1eb7ng co th\u1eaft l\u00ean h\u1ec7 tim m\u1ea1ch. C\u00e1c lo\u1ea1i thu\u1ed1c k\u00edch th\u00edch k\u00ea \u0111\u01a1n \u0111i\u1ec1u tr\u1ecb ch\u1ee9ng ADHD c\u0169ng ti\u1ec1m \u1ea9n nguy c\u01a1 t\u01b0\u01a1ng t\u1ef1. Tr\u00e1i tim b\u1ecb k\u00edch \u0111\u1ed9ng t\u1eeb hai h\u01b0\u1edbng c\u00f9ng l\u00fac, v\u00e0 r\u1ee7i ro n\u00e0y ho\u00e0n to\u00e0n c\u00f3 th\u1eadt tr\u00ean l\u00e2m s\u00e0ng.<\/p>\n\n\n\n

B\u1ee9c \u1ea3nh d\u01b0\u1edbi \u0111\u00e2y th\u1ec3 hi\u1ec7n t\u00ecnh hu\u1ed1ng \u0111\u1eddi th\u01b0\u1eddng khi\u1ebfn s\u1ef1 c\u1ed9ng d\u1ed3n nguy hi\u1ec3m n\u00e0y r\u1ea5t d\u1ec5 b\u1ecb b\u1ecf qu\u00ean:<\/p>\n\n\n\n

\"Coffee<\/figure>\n\n\n\n
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C\u00e1i B\u1eaby \u0110au \u0110\u1ea7u T\u00e1i Ph\u00e1t (Rebound Headache)<\/h2>\n\n\n\n

\u0110au \u0111\u1ea7u t\u00e1i ph\u00e1t (Rebound headache) l\u00e0 ph\u1ea7n c\u00e2u chuy\u1ec7n v\u1ec1 thu\u1ed1c gi\u1ea3m \u0111au ch\u1ee9a caffeine m\u00e0 h\u1ea7u nh\u01b0 kh\u00f4ng ai l\u01b0\u1eddng tr\u01b0\u1edbc \u2014 b\u1edfi v\u00ec tri\u1ec7u ch\u1ee9ng c\u1ee7a n\u00f3 gi\u1ed1ng h\u1ec7t nh\u01b0 ch\u00ednh c\u0103n b\u1ec7nh b\u1ea1n \u0111ang c\u1ed1 ch\u1eefa tr\u1ecb. C\u01a1 ch\u1ebf sinh l\u00fd r\u1ea5t r\u00f5 r\u00e0ng m\u1ed9t khi b\u1ea1n hi\u1ec3u \u0111\u01b0\u1ee3c chu k\u1ef3 m\u1ea1ch m\u00e1u: Caffeine l\u00e0m co c\u00e1c m\u1ea1ch m\u00e1u n\u00e3o \u0111\u1ec3 d\u1eadp t\u1eaft c\u01a1n \u0111au. Khi caffeine d\u1ea7n \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i kh\u1ecfi c\u01a1 th\u1ec3, c\u00e1c m\u1ea1ch m\u00e1u \u0111\u00f3 kh\u00f4ng ch\u1ec9 tr\u1edf v\u1ec1 tr\u1ea1ng th\u00e1i b\u00ecnh th\u01b0\u1eddng \u2014 m\u00e0 ch\u00fang ph\u1ea3n \u1ee9ng gi\u1eadt ng\u01b0\u1ee3c b\u1eb1ng c\u00e1ch gi\u00e3n n\u1edf r\u1ea5t nhanh. S\u1ef1 gi\u00e3n m\u1ea1ch \u0111\u1ed9t ng\u1ed9t \u0111\u00f3 l\u1ea1i ch\u00ednh l\u00e0 t\u00e1c nh\u00e2n k\u00edch th\u00edch th\u1ee5 c\u1ea3m \u0111au. C\u01a1n \u0111au \u0111\u1ea7u quay tr\u1edf l\u1ea1i kh\u00f4ng ph\u1ea3i l\u00e0 s\u1ef1 ti\u1ebfp di\u1ec5n c\u1ee7a c\u0103n b\u1ec7nh ban \u0111\u1ea7u. \u0110\u00f3 l\u00e0 c\u01a1n \u0111au \u0111\u1ea7u do h\u1ed9i ch\u1ee9ng cai thu\u1ed1c.<\/p>\n\n\n\n

C\u00e1i b\u1eaby kh\u00e9p l\u1ea1i \u1edf \u0111\u00e2y: c\u01a1n \u0111au \u0111\u1ea7u do cai thu\u1ed1c cho c\u1ea3m gi\u00e1c y h\u1ec7t nh\u01b0 c\u01a1n \u0111au \u0111\u1ea7u c\u0103ng th\u1eb3ng ho\u1eb7c c\u01a1n \u0111au n\u1eeda \u0111\u1ea7u \u0111\u00e3 kh\u1edfi \u0111\u1ea7u cho t\u1ea5t c\u1ea3. Th\u1ebf l\u00e0 b\u1ea1n l\u1ea1i v\u1edbi tay l\u1ea5y th\u00eam m\u1ed9t li\u1ec1u thu\u1ed1c n\u1eefa. V\u00f2ng l\u1eb7p ti\u1ebfp di\u1ec5n. Theo th\u1eddi gian, khu\u00f4n m\u1eabu n\u00e0y c\u1ee7ng c\u1ed1 th\u00e0nh b\u1ec7nh l\u00fd m\u00e0 c\u00e1c b\u00e1c s\u0129 g\u1ecdi l\u00e0 ch\u1ee9ng \u0110au \u0110\u1ea7u Do L\u1ea1m D\u1ee5ng Thu\u1ed1c (Medication-Overuse Headache – MOH).<\/p>\n\n\n\n

M\u1ed9t b\u00e0i b\u00e1o b\u00ecnh duy\u1ec7t tr\u00ean t\u1ea1p ch\u00ed Neurolog\u00eda<\/strong><\/u><\/a> gi\u1ea3i th\u00edch c\u01a1 ch\u1ebf th\u1ea7n kinh h\u1ecdc s\u00e2u xa \u0111\u1eb1ng sau v\u00f2ng lu\u1ea9n qu\u1ea9n n\u00e0y: Vi\u1ec7c s\u1eed d\u1ee5ng caffeine th\u01b0\u1eddng xuy\u00ean khi\u1ebfn c\u00e1c th\u1ee5 th\u1ec3 adenosine trong n\u00e3o b\u1ecb t\u0103ng sinh (up-regulate) \u2014 b\u1ed9 n\u00e3o b\u00f9 tr\u1eeb cho t\u00e1c \u0111\u1ed9ng phong t\u1ecfa c\u1ee7a caffeine b\u1eb1ng c\u00e1ch x\u00e2y d\u1ef1ng th\u00eam nhi\u1ec1u v\u1ecb tr\u00ed th\u1ee5 th\u1ec3 m\u1edbi. Khi l\u01b0\u1ee3ng caffeine t\u1ee5t gi\u1ea3m \u0111\u1ed9t ng\u1ed9t, m\u1ed9t l\u01b0\u1ee3ng l\u1edbn adenosine tr\u00e0n ng\u1eadp v\u00e0o c\u00e1c th\u1ee5 th\u1ec3 d\u00e0y \u0111\u1eb7c n\u00e0y, k\u00edch ho\u1ea1t s\u1ef1 gi\u00e3n m\u1ea1ch d\u1eef d\u1ed9i v\u00e0 ph\u00f3ng th\u00edch ph\u1ea3n \u1ee9ng vi\u00eam c\u1ee5c b\u1ed9. Nghi\u00ean c\u1ee9u c\u0169ng ghi nh\u1eadn s\u1ef1 t\u0103ng k\u00edch th\u00edch v\u1ecf n\u00e3o do c\u1ea1n ki\u1ec7t serotonin v\u00e0 s\u1ef1 nh\u1ea1y c\u1ea3m h\u00f3a trung \u01b0\u01a1ng c\u1ee7a h\u1ec7 th\u1ea7n kinh sinh ba, khi\u1ebfn c\u00e1c con \u0111\u01b0\u1eddng truy\u1ec1n t\u00edn hi\u1ec7u \u0111au lu\u00f4n \u1edf tr\u1ea1ng th\u00e1i tr\u1ef1c chi\u1ebfn \u2014 bi\u1ebfn b\u1ed9 n\u00e3o tr\u1edf n\u00ean nh\u1ea1y c\u1ea3m h\u01a1n v\u1edbi c\u01a1n \u0111au theo th\u1eddi gian, ch\u1ee9 kh\u00f4ng h\u1ec1 b\u1edbt \u0111i. C\u00e1c t\u00e1c gi\u1ea3 m\u00f4 t\u1ea3 c\u01a1 ch\u1ebf tr\u1ef1c ti\u1ebfp:<\/p>\n\n\n\n

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“…khi vi\u1ec7c ti\u00eau th\u1ee5 caffeine b\u1ecb gi\u00e1n \u0111o\u1ea1n \u0111\u1ed9t ng\u1ed9t, c\u00e1c th\u1ee5 th\u1ec3 adenosine tr\u1edf n\u00ean s\u1eb5n s\u00e0ng ti\u1ebfp nh\u1eadn, d\u1eabn \u0111\u1ebfn hi\u1ec7n t\u01b0\u1ee3ng gi\u00e3n m\u1ea1ch v\u00e0 gia t\u0103ng \u0111\u00e1ng k\u1ec3 l\u01b0u l\u01b0\u1ee3ng m\u00e1u l\u00ean n\u00e3o.”<\/em> \u2014 C\u00e1c t\u00e1c gi\u1ea3 b\u00e0i t\u1ed5ng quan, t\u1ea1p ch\u00ed y h\u1ecdc \u0111au \u0111\u1ea7u<\/p>\n\n<\/blockquote>\n\n\n\n

Ng\u01b0\u1ee1ng ch\u1ea9n \u0111o\u00e1n l\u00e2m s\u00e0ng theo ti\u00eau chu\u1ea9n ICHD-3 cho ch\u1ee9ng \u0111au \u0111\u1ea7u MOH ch\u1ec9 l\u00e0 10 ng\u00e0y m\u1ed7i th\u00e1ng \u0111\u1ed1i v\u1edbi c\u00e1c thu\u1ed1c gi\u1ea3m \u0111au ph\u1ed1i h\u1ee3p \u2014 ngh\u0129a l\u00e0 vi\u1ec7c d\u00f9ng thu\u1ed1c gi\u1ea3m \u0111au c\u00f3 caffeine kho\u1ea3ng 3 ng\u00e0y m\u1ed9t l\u1ea7n l\u00e0 \u0111\u00e3 \u0111\u1ee7 \u0111\u1ec3 r\u01a1i v\u00e0o nh\u00f3m nguy c\u01a1 b\u1ec7nh l\u00fd. L\u1eddi khuy\u00ean th\u1ef1c t\u1ebf \u0111\u1ec3 lu\u00f4n \u0111\u1ee9ng an to\u00e0n ngo\u00e0i v\u00f2ng xo\u00e1y n\u00e0y: kh\u00f4ng d\u00f9ng thu\u1ed1c gi\u1ea3m \u0111au ch\u1ee9a caffeine qu\u00e1 2 ho\u1eb7c 3 ng\u00e0y trong m\u1ed9t tu\u1ea7n.<\/p>\n\n\n\n

H\u1ed9i ch\u1ee9ng cai thu\u1ed1c \u0111\u1ea7y \u0111\u1ee7, n\u1ebfu b\u1ea1n d\u1eebng \u0111\u1ed9t ng\u1ed9t sau th\u1eddi gian d\u00f9ng th\u01b0\u1eddng xuy\u00ean, mang theo m\u1ed9t c\u1ee5m tri\u1ec7u ch\u1ee9ng kh\u00f3 ch\u1ecbu: \u0111au nh\u1ee9c \u0111\u1ea7u th\u1ea5u bu\u1ed1t t\u1eebng c\u01a1n, m\u1ec7t m\u1ecfi r\u00e3 r\u1eddi, c\u00e1u g\u1eaft v\u00e0 s\u01b0\u01a1ng m\u00f9 n\u00e3o l\u00e0 nh\u1eefng bi\u1ec3u hi\u1ec7n ph\u1ed5 bi\u1ebfn nh\u1ea5t, c\u00f3 th\u1ec3 k\u00e9o d\u00e0i v\u00e0i ng\u00e0y. C\u1ee5m tri\u1ec7u ch\u1ee9ng n\u00e0y th\u01b0\u1eddng b\u1ecb nh\u1ea7m l\u1eabn l\u00e0 b\u1ec7nh c\u1ea3m c\u00fam, c\u0103ng th\u1eb3ng c\u00f4ng vi\u1ec7c ho\u1eb7c b\u1ec7nh \u0111au \u0111\u1ea7u c\u0169 t\u00e1i ph\u00e1t n\u1eb7ng h\u01a1n \u2014 khi\u1ebfn ng\u01b0\u1eddi b\u1ec7nh l\u1ea1i v\u1ed9i v\u00e3 t\u00ecm \u0111\u1ebfn l\u1ecd thu\u1ed1c.<\/p>\n\n\n\n

M\u1ed1i nguy n\u00e0y kh\u00f4ng t\u00e1ch r\u1eddi v\u1edbi r\u1ee7i ro c\u1ed9ng d\u1ed3n li\u1ec1u l\u01b0\u1ee3ng. M\u1ed9t ng\u01b0\u1eddi th\u1ec9nh tho\u1ea3ng v\u01b0\u1ee3t m\u1ed1c 400mg m\u1ed7i ng\u00e0y do k\u1ebft h\u1ee3p Excedrin v\u1edbi c\u00e0 ph\u00ea c\u0169ng \u0111\u1ed3ng th\u1eddi \u0111ang nu\u00f4i d\u01b0\u1ee1ng nh\u1eefng bi\u1ebfn \u0111\u1ed5i th\u00edch nghi th\u1ea7n kinh l\u00e0m h\u1ea1 th\u1ea5p ng\u01b0\u1ee1ng ch\u1ecbu \u0111au c\u1ee7a h\u1ecd theo th\u1eddi gian. C\u1ea3 r\u1ee7i ro c\u1ea5p t\u00ednh l\u1eabn r\u1ee7i ro m\u1ea1n t\u00ednh \u0111\u1ec1u \u0111ang song h\u00e0nh ph\u00e1t tri\u1ec3n.<\/p>\n\n\n\n

C\u00e1ch Nh\u1eadn Di\u1ec7n Caffeine \u1ea8n Tr\u00ean Nh\u00e3n Thu\u1ed1c C\u1ee7a B\u1ea1n<\/h2>\n\n\n\n

B\u1ea3ng Th\u00f4ng tin D\u01b0\u1ee3c ph\u1ea9m (Drug Facts Label) l\u00e0 c\u00f4ng c\u1ee5 \u0111\u00e1ng tin c\u1eady nh\u1ea5t m\u00e0 b\u1ea1n c\u00f3 \u2014 v\u00e0 n\u00f3 hi\u1ec7n di\u1ec7n tr\u00ean m\u1ecdi h\u1ed9p thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n b\u1ea1n t\u1eebng mua. Ph\u1ea7n Ho\u1ea1t Ch\u1ea5t (Active Ingredients) lu\u00f4n n\u1eb1m \u1edf v\u1ecb tr\u00ed \u0111\u1ea7u ti\u00ean c\u1ee7a b\u1ea3ng Drug Facts, tr\u01b0\u1edbc c\u1ea3 h\u01b0\u1edbng d\u1eabn li\u1ec1u d\u00f9ng hay c\u1ea3nh b\u00e1o, li\u1ec7t k\u00ea t\u1eebng ho\u1ea1t ch\u1ea5t k\u00e8m h\u00e0m l\u01b0\u1ee3ng miligram ch\u00ednh x\u00e1c v\u00e0 c\u00f4ng d\u1ee5ng c\u00f4ng b\u1ed1. V\u1edbi caffeine, b\u1ea1n s\u1ebd th\u01b0\u1eddng th\u1ea5y ghi r\u00f5: “Caffeine 65 mg \u2014 ch\u1ea5t h\u1ed7 tr\u1ee3 gi\u1ea3m \u0111au” ho\u1eb7c “Caffeine 200 mg \u2014 ch\u1ea5t h\u1ed7 tr\u1ee3 t\u1ec9nh t\u00e1o”. C\u00f4ng b\u1ed1 n\u00e0y b\u1eaft bu\u1ed9c theo lu\u1eadt. N\u1ebfu c\u00f3 caffeine b\u00ean trong, nh\u00e0 s\u1ea3n xu\u1ea5t b\u1eaft bu\u1ed9c ph\u1ea3i ghi t\u00ean v\u00e0 \u0111\u1ecbnh l\u01b0\u1ee3ng r\u00f5 r\u00e0ng.<\/p>\n\n\n\n

Th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng v\u00e0 c\u00e1c s\u1ea3n ph\u1ea9m “t\u1ef1 nhi\u00ean” l\u1ea1i v\u1eadn h\u00e0nh theo quy \u0111\u1ecbnh kh\u00e1c. Ch\u00fang ch\u1ecbu s\u1ef1 \u0111i\u1ec1u ch\u1ec9nh c\u1ee7a b\u1ea3ng Th\u00f4ng tin B\u1ed5 sung (Supplement Facts) ch\u1ee9 kh\u00f4ng ph\u1ea3i Drug Facts, v\u00e0 lu\u1eadt cho ph\u00e9p li\u1ec7t k\u00ea caffeine d\u01b0\u1edbi c\u00e1c danh ph\u00e1p th\u1ef1c v\u1eadt h\u1ecdc m\u00e0 kh\u00f4ng c\u1ea7n ghi r\u00f5 ch\u1eef “caffeine”. B\u1ed1n c\u00e1i t\u00ean ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ea7n c\u1ea3nh gi\u00e1c: guarana, chi\u1ebft xu\u1ea5t tr\u00e0 xanh, yerba mate v\u00e0 h\u1ea1t kola. C\u1ea3 b\u1ed1n lo\u1ea1i n\u00e0y \u0111\u1ec1u cung c\u1ea5p l\u01b0\u1ee3ng caffeine th\u1ef1c s\u1ef1. Kh\u00f4ng c\u00e1i t\u00ean n\u00e0o t\u1ea1o cho b\u1ea1n ph\u1ea3n x\u1ea1 c\u1ea3nh gi\u00e1c nh\u01b0 khi nh\u00ecn th\u1ea5y ch\u1eef “caffeine” in th\u1eb3ng th\u1eebng. Trung t\u00e2m Qu\u1ed1c gia v\u1ec1 S\u1ee9c kh\u1ecfe B\u1ed5 sung v\u00e0 T\u00edch h\u1ee3p Hoa K\u1ef3 (NCCIH)<\/strong><\/u><\/a> nh\u1ea5n m\u1ea1nh:<\/p>\n\n\n\n

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“Th\u1ef1c ph\u1ea9m b\u1ed5 sung c\u00f3 th\u1ec3 ch\u1ee9a c\u00e1c th\u00e0nh ph\u1ea7n kh\u00f4ng ph\u1ea3i l\u00e0 th\u1ea3o m\u1ed9c, ch\u1eb3ng h\u1ea1n nh\u01b0 vitamin, kho\u00e1ng ch\u1ea5t, axit amin v\u00e0 caffeine.”<\/em> \u2014 Trung t\u00e2m Qu\u1ed1c gia v\u1ec1 S\u1ee9c kh\u1ecfe B\u1ed5 sung v\u00e0 T\u00edch h\u1ee3p (NCCIH thu\u1ed9c NIH)<\/p>\n\n<\/blockquote>\n\n\n\n

\u0110\u1ed1i v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c k\u00ea \u0111\u01a1n, vi\u1ec7c ki\u1ec3m tra nh\u00e3n thu\u1ed1c kh\u00f4ng ph\u1ea3i l\u00fac n\u00e0o c\u0169ng \u0111\u01a1n gi\u1ea3n theo m\u1eabu chu\u1ea9n. M\u1ed9t s\u1ed1 thu\u1ed1c k\u00ea \u0111\u01a1n tr\u1ecb \u0111au n\u1eeda \u0111\u1ea7u v\u00e0 m\u1ed9t v\u00e0i c\u00f4ng th\u1ee9c tr\u1ecb c\u1ea3m c\u00fam c\u00f3 ch\u1ee9a caffeine, nh\u01b0ng bao b\u00ec c\u00f3 th\u1ec3 kh\u00f4ng l\u00e0m n\u1ed5i b\u1eadt \u0111i\u1ec1u \u0111\u00f3. \u0110\u1ed9ng th\u00e1i \u0111\u00e1ng tin c\u1eady nh\u1ea5t l\u00e0 h\u1ecfi tr\u1ef1c ti\u1ebfp d\u01b0\u1ee3c s\u0129 c\u1ee7a b\u1ea1n: h\u00e3y \u0111\u1eb7t c\u00e2u h\u1ecfi c\u1ee5 th\u1ec3 “Thu\u1ed1c n\u00e0y c\u00f3 ch\u1ee9a caffeine kh\u00f4ng, v\u00e0 n\u00f3 c\u00f3 t\u01b0\u01a1ng t\u00e1c v\u1edbi caffeine t\u1eeb c\u00e0 ph\u00ea ho\u1eb7c \u0111\u1ed3 u\u1ed1ng kh\u00e1c kh\u00f4ng?”. D\u01b0\u1ee3c s\u0129 c\u0169ng c\u00f3 th\u1ec3 c\u1ea3nh b\u00e1o b\u1ea1n v\u1ec1 c\u00e1c t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP1A2 nh\u01b0 ciprofloxacin hay thu\u1ed1c tr\u00e1nh thai l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh thanh th\u1ea3i.<\/p>\n\n\n\n

Th\u00f3i quen \u0111\u01a1n gi\u1ea3n nh\u1ea5t \u0111\u1ec3 x\u00e2y d\u1ef1ng: m\u1ed9t ph\u00e9p c\u1ed9ng nh\u1ea9m miligram li\u00ean t\u1ee5c. C\u1ed9ng l\u01b0\u1ee3ng caffeine t\u1eeb m\u1ed7i vi\u00ean thu\u1ed1c b\u1ea1n u\u1ed1ng, r\u1ed3i c\u1ed9ng th\u00eam l\u01b0\u1ee3ng c\u00e0 ph\u00ea, tr\u00e0 v\u00e0 n\u01b0\u1edbc ng\u1ecdt trong c\u00f9ng khung th\u1eddi gian. T\u1ed5ng s\u1ed1 m\u1edbi l\u00e0 \u0111i\u1ec1u quy\u1ebft \u0111\u1ecbnh, kh\u00f4ng ph\u1ea3i t\u1eebng ngu\u1ed3n ri\u00eang l\u1ebb. H\u1ea7u h\u1ebft nh\u1eefng ng\u01b0\u1eddi ph\u00e1t hi\u1ec7n m\u00ecnh \u0111\u00e3 v\u01b0\u1ee3t ng\u01b0\u1ee1ng 400mg kh\u00f4ng l\u00e0m \u0111i\u1ec1u g\u00ec qu\u00e1 \u0111\u00e0 \u2014 h\u1ecd ch\u1ec9 v\u1eeba l\u00e0m ph\u00e9p t\u00ednh cho nh\u1eefng con s\u1ed1 m\u00e0 tr\u01b0\u1edbc \u0111\u00e2y h\u1ecd ch\u01b0a t\u1eebng gh\u00e9p l\u1ea1i c\u00f9ng nhau.<\/p>\n\n\n\n

Th\u00eam m\u1ed9t chi ti\u1ebft \u00edt ai \u0111\u1ec1 c\u1eadp: caffeine c\u00f3 th\u1ec3 l\u00e0m sai l\u1ec7ch k\u1ebft qu\u1ea3 c\u1ee7a m\u1ed9t s\u1ed1 x\u00e9t nghi\u1ec7m m\u00e1u, t\u1ea1o ra c\u00e1c ch\u1ec9 s\u1ed1 gi\u1ea3 khi\u1ebfn b\u1ea1n ph\u1ea3i l\u00e0m th\u00eam c\u00e1c x\u00e9t nghi\u1ec7m th\u0103m d\u00f2 kh\u00f4ng c\u1ea7n thi\u1ebft. N\u1ebfu b\u1ea1n c\u00f3 l\u1ecbch x\u00e9t nghi\u1ec7m m\u00e1u, h\u00e3y th\u00f4ng b\u00e1o cho nh\u00e2n vi\u00ean y t\u1ebf v\u1ec1 b\u1ea5t k\u1ef3 lo\u1ea1i thu\u1ed1c n\u00e0o c\u00f3 ch\u1ee9a caffeine b\u1ea1n \u0111\u00e3 u\u1ed1ng g\u1ea7n \u0111\u00f3 \u2014 ch\u1ee9 kh\u00f4ng ch\u1ec9 ri\u00eang vi\u1ec7c b\u1ea1n \u0111\u00e3 \u0103n hay u\u1ed1ng g\u00ec s\u00e1ng h\u00f4m \u1ea5y.<\/p>\n\n\n\n

Nh\u1eefng \u0110i\u1ec3m C\u1ed1t L\u00f5i V\u1ec1 Caffeine Trong Thu\u1ed1c<\/h2>\n\n\n\n
    \n
  • Caffeine trong thu\u1ed1c gi\u1ea3m \u0111au v\u1eadn h\u00e0nh qua hai c\u01a1 ch\u1ebf: l\u00e0m co th\u1eaft m\u1ea1ch m\u00e1u n\u00e3o v\u00e0 t\u0103ng t\u1ed1c \u0111\u1ed9 h\u1ea5p thu c\u00e1c ho\u1ea1t ch\u1ea5t gi\u1ea3m \u0111au nh\u01b0 paracetamol v\u00e0 aspirin.<\/li>\n\n\n\n
  • M\u1ed9t li\u1ec1u 2 vi\u00ean Excedrin ti\u00eau chu\u1ea9n cung c\u1ea5p 130mg caffeine \u2014 nhi\u1ec1u h\u01a1n m\u1ed9t t\u00e1ch c\u00e0 ph\u00ea th\u00f4ng th\u01b0\u1eddng \u2014 tr\u01b0\u1edbc khi t\u00ednh \u0111\u1ebfn b\u1ea5t k\u1ef3 \u0111\u1ed3 u\u1ed1ng n\u00e0o kh\u00e1c.<\/li>\n\n\n\n
  • U\u1ed1ng m\u1ed9t ly c\u00e0 ph\u00ea l\u1edbn c\u00f9ng l\u00fac v\u1edbi thu\u1ed1c gi\u1ea3m \u0111au ch\u1ee9a caffeine c\u00f3 th\u1ec3 \u0111\u1ea9y t\u1ed5ng l\u01b0\u1ee3ng n\u1ea1p trong m\u1ed9t l\u1ea7n l\u00ean h\u01a1n 430mg, v\u01b0\u1ee3t ng\u01b0\u1ee1ng an to\u00e0n 400mg c\u1ea3 ng\u00e0y c\u1ee7a FDA ch\u1ec9 trong m\u1ed9t bu\u1ed5i s\u00e1ng.<\/li>\n\n\n\n
  • Ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a ch\u1eadm qua enzyme CYP1A2 \u2014 chi\u1ebfm kho\u1ea3ng 25% d\u00e2n s\u1ed1 \u2014 \u0111\u00e0o th\u1ea3i caffeine ch\u1eadm h\u01a1n t\u1edbi 4 l\u1ea7n, khi\u1ebfn c\u00f9ng m\u1ed9t li\u1ec1u l\u01b0\u1ee3ng tr\u1edf n\u00ean r\u1ee7i ro h\u01a1n nhi\u1ec1u \u0111\u1ed1i v\u1edbi h\u1ecd.<\/li>\n\n\n\n
  • D\u00f9ng thu\u1ed1c gi\u1ea3m \u0111au ch\u1ee9a caffeine nhi\u1ec1u h\u01a1n 2 ho\u1eb7c 3 ng\u00e0y m\u1ed7i tu\u1ea7n c\u00f3 th\u1ec3 k\u00edch ho\u1ea1t ch\u1ee9ng \u0111au \u0111\u1ea7u do l\u1ea1m d\u1ee5ng thu\u1ed1c (MOH) \u2014 m\u1ed9t v\u00f2ng l\u1eb7p \u0111au do cai thu\u1ed1c gi\u1ed1ng h\u1ec7t c\u01a1n \u0111au ban \u0111\u1ea7u.<\/li>\n\n\n\n
  • B\u1ea3ng Drug Facts lu\u00f4n ghi r\u00f5 t\u00ean caffeine v\u00e0 s\u1ed1 miligram c\u1ee5 th\u1ec3; v\u1edbi th\u1ef1c ph\u1ea9m b\u1ed5 sung, h\u00e3y c\u1ea3nh gi\u00e1c v\u1edbi c\u00e1c ngu\u1ed3n th\u1ea3o m\u1ed9c nh\u01b0 guarana, chi\u1ebft xu\u1ea5t tr\u00e0 xanh, yerba mate v\u00e0 h\u1ea1t kola.<\/li>\n<\/ul>\n\n\n\n

    Nh\u1eefng C\u00e2u H\u1ecfi Th\u01b0\u1eddng G\u1eb7p V\u1ec1 Caffeine Trong D\u01b0\u1ee3c Ph\u1ea9m<\/h2>\n\n\n\n

    Nh\u1eefng s\u1ea3n ph\u1ea9m th\u00f4ng th\u01b0\u1eddng n\u00e0o ch\u1ee9a caffeine m\u00e0 h\u1ea7u h\u1ebft m\u1ecdi ng\u01b0\u1eddi kh\u00f4ng ng\u1edd t\u1edbi?<\/h3>\n\n\n\n

    B\u00ean c\u1ea1nh c\u00e0 ph\u00ea v\u00e0 n\u01b0\u1edbc t\u0103ng l\u1ef1c, caffeine xu\u1ea5t hi\u1ec7n trong Excedrin, Midol Complete, m\u1ed9t s\u1ed1 c\u00f4ng th\u1ee9c DayQuil v\u00e0 Theraflu, vi\u00ean u\u1ed1ng NoDoz, Vivarin, c\u00f9ng nhi\u1ec1u lo\u1ea1i th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng gi\u1ea3m c\u00e2n v\u00e0 t\u0103ng l\u1ef1c th\u1ea3o m\u1ed9c li\u1ec7t k\u00ea d\u01b0\u1edbi t\u00ean guarana hay chi\u1ebft xu\u1ea5t tr\u00e0 xanh. Ph\u00e2n t\u00edch ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean 63 s\u1ea3n ph\u1ea9m gi\u1ea3m c\u00e2n v\u00e0 c\u1ea3m c\u00fam ph\u00e1t hi\u1ec7n kho\u1ea3ng 52% c\u00f3 ch\u1ee9a caffeine.<\/p>\n\n\n\n

    Nh\u1eefng lo\u1ea1i thu\u1ed1c n\u00e0o tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng n\u00ean k\u1ebft h\u1ee3p c\u00f9ng caffeine t\u1eeb c\u00e0 ph\u00ea hay c\u00e1c ngu\u1ed3n kh\u00e1c?<\/h3>\n\n\n\n

    S\u1ef1 k\u1ebft h\u1ee3p r\u1ee7i ro cao nh\u1ea5t li\u00ean quan \u0111\u1ebfn c\u00e1c thu\u1ed1c th\u00f4ng m\u0169i ch\u1ee9a pseudoephedrine, thu\u1ed1c k\u00edch th\u00edch k\u00ea \u0111\u01a1n tr\u1ecb ADHD v\u00e0 kh\u00e1ng sinh nh\u00f3m fluoroquinolone nh\u01b0 ciprofloxacin \u2014 ciprofloxacin l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh \u0111\u00e0o th\u1ea3i caffeine qua enzyme CYP1A2, khi\u1ebfn l\u01b0\u1ee3ng caffeine t\u1eeb thu\u1ed1c v\u00e0 c\u00e0 ph\u00ea l\u01b0u l\u1ea1i trong m\u00e1u l\u00e2u h\u01a1n nhi\u1ec1u so v\u1edbi b\u00ecnh th\u01b0\u1eddng.<\/p>\n\n\n\n

    Caffeine trong thu\u1ed1c c\u00f3 l\u00e0m \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m m\u00e1u kh\u00f4ng?<\/h3>\n\n\n\n

    C\u00f3 \u2014 caffeine c\u00f3 th\u1ec3 l\u00e0m bi\u1ebfn \u0111\u1ed9ng m\u1ed9t s\u1ed1 ch\u1ec9 s\u1ed1 sinh h\u00f3a, t\u1ea1o ra c\u00e1c k\u1ebft qu\u1ea3 sai l\u1ec7ch v\u00e0 d\u1eabn \u0111\u1ebfn c\u00e1c x\u00e9t nghi\u1ec7m theo d\u00f5i kh\u00f4ng c\u1ea7n thi\u1ebft. N\u1ebfu b\u1ea1n \u0111\u00e3 u\u1ed1ng thu\u1ed1c ch\u1ee9a caffeine tr\u01b0\u1edbc khi l\u1ea5y m\u00e1u, h\u00e3y th\u00f4ng b\u00e1o c\u1ee5 th\u1ec3 cho b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb ho\u1eb7c k\u1ef9 thu\u1eadt vi\u00ean ph\u00f2ng x\u00e9t nghi\u1ec7m.<\/p>\n\n\n\n

    Caffeine trong thu\u1ed1c gi\u1ea3m \u0111au c\u00f3 g\u00e2y l\u1ec7 thu\u1ed9c gi\u1ed1ng nh\u01b0 th\u00f3i quen u\u1ed1ng c\u00e0 ph\u00ea h\u00e0ng ng\u00e0y kh\u00f4ng?<\/h3>\n\n\n\n

    V\u1ec1 m\u1eb7t ch\u1ee9c n\u0103ng l\u00e0 c\u00f3. Vi\u1ec7c s\u1eed d\u1ee5ng th\u01b0\u1eddng xuy\u00ean c\u00e1c thu\u1ed1c gi\u1ea3m \u0111au c\u00f3 caffeine d\u1eabn \u0111\u1ebfn s\u1ef1 t\u0103ng sinh c\u00e1c th\u1ee5 th\u1ec3 adenosine \u2014 ch\u00ednh l\u00e0 c\u01a1 ch\u1ebf th\u00edch nghi th\u1ea7n kinh khi\u1ebfn ng\u01b0\u1eddi nghi\u1ec7n c\u00e0 ph\u00ea th\u1ea5y cho\u00e1ng v\u00e1ng n\u1ebfu thi\u1ebfu t\u00e1ch c\u00e0 ph\u00ea s\u00e1ng. Ng\u01b0\u1ee1ng ch\u1ea9n \u0111o\u00e1n \u0111au \u0111\u1ea7u do l\u1ea1m d\u1ee5ng thu\u1ed1c theo ICHD-3 ch\u1ec9 l\u00e0 10 ng\u00e0y d\u00f9ng m\u1ed7i th\u00e1ng.<\/p>\n\n\n\n

    Gi\u1edbi h\u1ea1n 400mg caffeine m\u1ed7i ng\u00e0y c\u00f3 an to\u00e0n cho t\u1ea5t c\u1ea3 m\u1ecdi ng\u01b0\u1eddi kh\u00f4ng?<\/h3>\n\n\n\n

    \u0110\u00f3 l\u00e0 m\u1ee9c trung b\u00ecnh d\u00e2n s\u1ed1 d\u00e0nh cho ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh kh\u1ecfe m\u1ea1nh kh\u00f4ng mang thai \u2014 kh\u00f4ng ph\u1ea3i ng\u01b0\u1ee1ng c\u00e1 nh\u00e2n tuy\u1ec7t \u0111\u1ed1i. Nh\u00f3m chuy\u1ec3n h\u00f3a ch\u1eadm qua enzyme CYP1A2 \u0111\u00e0o th\u1ea3i caffeine ch\u1eadm h\u01a1n t\u1edbi 4 l\u1ea7n, v\u00e0 ph\u1ee5 n\u1eef mang thai \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o \u1edf m\u1ee9c d\u01b0\u1edbi 200mg m\u1ed7i ng\u00e0y. Gi\u1edbi h\u1ea1n th\u1ef1c s\u1ef1 ph\u1ee5 thu\u1ed9c v\u00e0o c\u01a1 \u0111\u1ecba di truy\u1ec1n, t\u00ecnh tr\u1ea1ng d\u00f9ng thu\u1ed1c v\u00e0 giai \u0111o\u1ea1n cu\u1ed9c s\u1ed1ng c\u1ee7a b\u1ea1n.<\/p>\n\n\n\n

    T\u00f4i c\u00f3 th\u1ec3 u\u1ed1ng thu\u1ed1c gi\u1ea3m \u0111au ch\u1ee9a caffeine n\u1ebfu \u0111ang d\u00f9ng thu\u1ed1c tr\u00e1nh thai kh\u00f4ng?<\/h3>\n\n\n\n

    B\u1ea1n c\u00f3 th\u1ec3 d\u00f9ng, nh\u01b0ng c\u1ea7n l\u01b0u \u00fd r\u1eb1ng thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng \u1ee9c ch\u1ebf enzyme CYP1A2 v\u00e0 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh ph\u00e2n h\u1ee7y caffeine, do \u0111\u00f3 l\u01b0\u1ee3ng caffeine trong vi\u00ean thu\u1ed1c s\u1ebd l\u01b0u l\u1ea1i trong c\u01a1 th\u1ec3 l\u00e2u h\u01a1n b\u00ecnh th\u01b0\u1eddng. Gi\u1eef t\u1ed5ng l\u01b0\u1ee3ng caffeine th\u1ea5p h\u01a1n trong nh\u1eefng ng\u00e0y b\u1ea1n c\u1ea7n u\u1ed1ng thu\u1ed1c l\u00e0 c\u00e1ch qu\u1ea3n l\u00fd kh\u00f4n ngoan.<\/p>\n\n\n\n

    Caffeine c\u00f3 t\u01b0\u01a1ng t\u00e1c v\u1edbi Lexapro hay c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m kh\u00e1c kh\u00f4ng?<\/h3>\n\n\n\n

    B\u1ea3n th\u00e2n Lexapro (escitalopram) kh\u00f4ng ch\u1ee9a caffeine, nh\u01b0ng caffeine n\u1ea1p nhi\u1ec1u c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam ch\u1ee9ng lo \u00e2u v\u00e0 l\u00e0m gi\u00e1n \u0111o\u1ea1n ch\u1ea5t l\u01b0\u1ee3ng gi\u1ea5c ng\u1ee7 \u2014 hai ph\u01b0\u01a1ng di\u1ec7n m\u00e0 c\u00e1c thu\u1ed1c SSRI nh\u01b0 Lexapro \u0111ang n\u1ed7 l\u1ef1c \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 t\u00e1i thi\u1ebft l\u1eadp s\u1ef1 \u1ed5n \u0111\u1ecbnh. L\u01b0\u1ee3ng caffeine cao c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t lo \u00e2u c\u1ee7a thu\u1ed1c, v\u00ec v\u1eady b\u1ea1n n\u00ean trao \u0111\u1ed5i th\u1eb3ng th\u1eafn v\u1edbi b\u00e1c s\u0129 k\u00ea \u0111\u01a1n v\u1ec1 th\u00f3i quen d\u00f9ng caffeine c\u1ee7a m\u00ecnh.<\/p>\n\n\n\n

    L\u00e0m th\u1ebf n\u00e0o \u0111\u1ec3 ph\u00e2n bi\u1ec7t \u0111au \u0111\u1ea7u do cai caffeine v\u1edbi \u0111au \u0111\u1ea7u c\u0103ng th\u1eb3ng th\u00f4ng th\u01b0\u1eddng?<\/h3>\n\n\n\n

    Th\u1eddi \u0111i\u1ec3m xu\u1ea5t hi\u1ec7n l\u00e0 d\u1ea5u hi\u1ec7u ph\u00e2n \u0111\u1ecbnh r\u00f5 r\u00e0ng nh\u1ea5t: \u0111au \u0111\u1ea7u do cai thu\u1ed1c th\u01b0\u1eddng xu\u1ea5t hi\u1ec7n \u0111\u1ec1u \u0111\u1eb7n trong kho\u1ea3ng 12 \u0111\u1ebfn 24 gi\u1edd sau li\u1ec1u caffeine cu\u1ed1i c\u00f9ng v\u00e0 th\u01b0\u1eddng \u0111i k\u00e8m v\u1edbi c\u1ea3m gi\u00e1c m\u1ec7t m\u1ecfi, u\u1ec3 o\u1ea3i, c\u00e1u g\u1eaft v\u00e0 kh\u00f3 t\u1eadp trung. Trong khi \u0111\u00f3, c\u01a1n \u0111au \u0111\u1ea7u c\u0103ng th\u1eb3ng th\u01b0\u1eddng t\u00edch t\u1ee5 d\u1ea7n theo \u00e1p l\u1ef1c c\u00f4ng vi\u1ec7c, t\u01b0 th\u1ebf ng\u1ed3i sai ho\u1eb7c co c\u1ee9ng c\u01a1 b\u1eafp m\u00e0 kh\u00f4ng tu\u00e2n theo chu k\u1ef3 th\u1eddi gian c\u1ee7a caffeine.<\/p>\n\n\n\n

    T\u00e0i Li\u1ec7u Tham Kh\u1ea3o<\/h2>\n\n\n\n
      \n
    • Caffeine as an Analgesic Adjuvant – ScienceDirect (T\u1ed5ng quan D\u01b0\u1ee3c l\u00fd h\u1ecdc)<\/li>\n\n\n\n
    • Excedrin Fixed Combination Drug Study – Frontiers in Pharmacology (Voicu v\u00e0 c\u1ed9ng s\u1ef1)<\/li>\n\n\n\n
    • Laboratory Analysis of Caffeine in Weight-Loss and Cold S\u1ea3n Ph\u1ea9ms – USDA ARS<\/li>\n\n\n\n
    • FDA Consumer Update: How Much Caffeine Is Too Much – FDA.gov<\/li>\n\n\n\n
    • Caffeine and Headache: Specific Remarks (Neurolog\u00eda, English Edition) – ScienceDirect<\/li>\n\n\n\n
    • Dietary Supplements and Herbal Medicines – NCCIH (NIH)<\/li>\n<\/ul>\n\n\n\n